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Our Division is one of the top centers for diagnosis, treatment, and identification of parathyroid disorders.
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Primary Hyperparathyroidism: Neurocognitive Features
Primary hyperparathyroidism (PHPT) is a common condition caused by over-activity of the parathyroid gland(s), which leads to elevated parathyroid hormone and blood calcium levels. Many PHPT patients report nonspecific problems with thinking and memory. Results from this study will contribute towards development of surgical guidelines for the management of PHPT patients with cognitive symptoms. If you would like to participate or are interested in learning more about the study, please contact our study coordinator.
Occult Nephrolithiasis in Primary Hyperparathyroidism
Primary hyperparathyroidism (PHPT) is a relatively common endocrine disorder in which the parathyroid glands become overactive leading to high blood calcium and parathyroid hormone levels. Today, most patients with PHPT are asymptomatic and are diagnosed based on mild hypercalcemia noted on routine lab work. Symptomatic kidney stones (nephrolithiasis) affect about 15-20% of patients with PHPT and such patients are advised to have parathyroidectomy (PTX). This study will determine the prevalence of occult nephrolithiasis through a prospective chart review and will also clarify what disease features are associated with this finding.
Genetics of Plate- or Rod-like Bone Phenotype
The purpose of this study is to identify the genetic factors (genes) that cause a person’s trabecular bone to be more plate- versus rod-like. Results of this study can help increase understanding of the genetic basis for the observed differences in bone structure and strength between different races.
Cystic fibrosis related bone disease
Recent advances have improved the management of cystic fibrosis and increased the life expectancy for patients. However, there has been an increase in other medical complications such as bone disease. We are recruiting women and men with and without cystic fibrosis.
Treatment of Vitamin D Deficiency in patients with PHPT
Many patients with mild Primary Hyperparathyroidism (PHPT) have Vitamin D deficiency. Both PHPT and Vitamin D deficiency can weaken bones and cause osteoporosis. We are recruiting women and men with PHPT. Learn more.